Name | Glycine anhydride |
Synonyms | Oxiracetam-1 Cyclo(-Gly-Gly) Dioxo Piperazine 2,5-Piperazindion Glycine anhydride 2,5-Dioxopiperazin 2,5-Piperazinedione piperazine-2,3-dione 2,5-Diketopiperazine piperazine-2,5-dione Cyclic(glycylglycyl) PIPERAZINE-2,5-DIONE Glycine EP Impurity B 2,5-Dioxopiperazine lactam alpha,gamma-Diacipiperazine 2,5-Piperazinedione,(Glycine anhydride) |
CAS | 106-57-0 |
EINECS | 203-411-5 |
InChI | InChI=1/C4H6N2O2/c7-3-4(8)6-2-1-5-3/h1-2H2,(H,5,7)(H,6,8) |
InChIKey | BXRNXXXXHLBUKK-UHFFFAOYSA-N |
Molecular Formula | C4H6N2O2 |
Molar Mass | 114.1 |
Density | 1.3565 (rough estimate) |
Melting Point | >300 °C (lit.) |
Boling Point | 213.59°C (rough estimate) |
Water Solubility | Soluble in water (142mg/L). |
Solubility | 142g/l |
Appearance | White to slightly yellow crystalline powder |
Color | White to slightly yellow |
Merck | 14,7466 |
BRN | 112112 |
pKa | 12.88±0.20(Predicted) |
Storage Condition | Store below +30°C. |
Refractive Index | 1.4487 (estimate) |
MDL | MFCD00006009 |
Physical and Chemical Properties | Crystals in the form of flakes or needles. Melting point 31-312 deg C (decomposition),260 deg C sublimation. Soluble in hot water, with weak alkaline. |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
RTECS | TL6325250 |
TSCA | Yes |
HS Code | 29335990 |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
Use | Used as a biochemical reagent. Glycylglycine can be obtained by hydrolysis by alkali, acid or hot water. |
production method | is obtained by condensation of glycine. Glycine and ethylenediamine are mixed at 1:5, stirred and heated, reacted at 174-176 ℃ for 50min, then placed in an ice chamber for over recognition, filtered out crystals, washed with methanol, and dried to obtain glycyl anhydride. It can also be prepared by condensation of glycine in dehydrated glycerol. |